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	<title>E v o l u t i o n</title>
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		<title>E v o l u t i o n</title>
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		<item>
		<title>Aging</title>
		<link>http://arunabhsingh.wordpress.com/2007/05/13/aging/</link>
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		<pubDate>Sun, 13 May 2007 06:07:12 +0000</pubDate>
		<dc:creator>Arunabh Singh</dc:creator>
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		<description><![CDATA[Aging could be a evolutionary process to reduce the competition within the species.<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=arunabhsingh.wordpress.com&amp;blog=256414&amp;post=35&amp;subd=arunabhsingh&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p>Aging could be a evolutionary process to reduce the competition within the species.</p>
<br /><img alt="" border="0" src="http://feeds.wordpress.com/1.0/categories/arunabhsingh.wordpress.com/35/" /> <img alt="" border="0" src="http://feeds.wordpress.com/1.0/tags/arunabhsingh.wordpress.com/35/" /> <a rel="nofollow" href="http://feeds.wordpress.com/1.0/gocomments/arunabhsingh.wordpress.com/35/"><img alt="" border="0" src="http://feeds.wordpress.com/1.0/comments/arunabhsingh.wordpress.com/35/" /></a> <a rel="nofollow" href="http://feeds.wordpress.com/1.0/godelicious/arunabhsingh.wordpress.com/35/"><img alt="" border="0" src="http://feeds.wordpress.com/1.0/delicious/arunabhsingh.wordpress.com/35/" /></a> <a rel="nofollow" href="http://feeds.wordpress.com/1.0/gofacebook/arunabhsingh.wordpress.com/35/"><img alt="" border="0" src="http://feeds.wordpress.com/1.0/facebook/arunabhsingh.wordpress.com/35/" /></a> <a rel="nofollow" href="http://feeds.wordpress.com/1.0/gotwitter/arunabhsingh.wordpress.com/35/"><img alt="" border="0" src="http://feeds.wordpress.com/1.0/twitter/arunabhsingh.wordpress.com/35/" /></a> <a rel="nofollow" href="http://feeds.wordpress.com/1.0/gostumble/arunabhsingh.wordpress.com/35/"><img alt="" border="0" src="http://feeds.wordpress.com/1.0/stumble/arunabhsingh.wordpress.com/35/" /></a> <a rel="nofollow" href="http://feeds.wordpress.com/1.0/godigg/arunabhsingh.wordpress.com/35/"><img alt="" border="0" src="http://feeds.wordpress.com/1.0/digg/arunabhsingh.wordpress.com/35/" /></a> <a rel="nofollow" href="http://feeds.wordpress.com/1.0/goreddit/arunabhsingh.wordpress.com/35/"><img alt="" border="0" src="http://feeds.wordpress.com/1.0/reddit/arunabhsingh.wordpress.com/35/" /></a> <img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=arunabhsingh.wordpress.com&amp;blog=256414&amp;post=35&amp;subd=arunabhsingh&amp;ref=&amp;feed=1" width="1" height="1" />]]></content:encoded>
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			<media:title type="html">Arunabh</media:title>
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		<title>GOD</title>
		<link>http://arunabhsingh.wordpress.com/2007/05/13/god/</link>
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		<pubDate>Sun, 13 May 2007 05:43:22 +0000</pubDate>
		<dc:creator>Arunabh Singh</dc:creator>
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		<description><![CDATA[God only exists in the mind of the weak and fearful&#8230;&#8230;<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=arunabhsingh.wordpress.com&amp;blog=256414&amp;post=34&amp;subd=arunabhsingh&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p>God only exists in the mind of the weak and fearful&#8230;&#8230;</p>
<br /><img alt="" border="0" src="http://feeds.wordpress.com/1.0/categories/arunabhsingh.wordpress.com/34/" /> <img alt="" border="0" src="http://feeds.wordpress.com/1.0/tags/arunabhsingh.wordpress.com/34/" /> <a rel="nofollow" href="http://feeds.wordpress.com/1.0/gocomments/arunabhsingh.wordpress.com/34/"><img alt="" border="0" src="http://feeds.wordpress.com/1.0/comments/arunabhsingh.wordpress.com/34/" /></a> <a rel="nofollow" href="http://feeds.wordpress.com/1.0/godelicious/arunabhsingh.wordpress.com/34/"><img alt="" border="0" src="http://feeds.wordpress.com/1.0/delicious/arunabhsingh.wordpress.com/34/" /></a> <a rel="nofollow" href="http://feeds.wordpress.com/1.0/gofacebook/arunabhsingh.wordpress.com/34/"><img alt="" border="0" src="http://feeds.wordpress.com/1.0/facebook/arunabhsingh.wordpress.com/34/" /></a> <a rel="nofollow" href="http://feeds.wordpress.com/1.0/gotwitter/arunabhsingh.wordpress.com/34/"><img alt="" border="0" src="http://feeds.wordpress.com/1.0/twitter/arunabhsingh.wordpress.com/34/" /></a> <a rel="nofollow" href="http://feeds.wordpress.com/1.0/gostumble/arunabhsingh.wordpress.com/34/"><img alt="" border="0" src="http://feeds.wordpress.com/1.0/stumble/arunabhsingh.wordpress.com/34/" /></a> <a rel="nofollow" href="http://feeds.wordpress.com/1.0/godigg/arunabhsingh.wordpress.com/34/"><img alt="" border="0" src="http://feeds.wordpress.com/1.0/digg/arunabhsingh.wordpress.com/34/" /></a> <a rel="nofollow" href="http://feeds.wordpress.com/1.0/goreddit/arunabhsingh.wordpress.com/34/"><img alt="" border="0" src="http://feeds.wordpress.com/1.0/reddit/arunabhsingh.wordpress.com/34/" /></a> <img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=arunabhsingh.wordpress.com&amp;blog=256414&amp;post=34&amp;subd=arunabhsingh&amp;ref=&amp;feed=1" width="1" height="1" />]]></content:encoded>
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		<title>HGH—Human Growth Hormone</title>
		<link>http://arunabhsingh.wordpress.com/2007/04/10/hgh%e2%80%94human-growth-hormone/</link>
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		<pubDate>Tue, 10 Apr 2007 09:38:37 +0000</pubDate>
		<dc:creator>Arunabh Singh</dc:creator>
				<category><![CDATA[Evolution]]></category>

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		<description><![CDATA[HGH—human growth hormoneIt is your pituitary gland that produces the ever so important HGH that your body needs. Unfortunately this gland does not secrete this as much in your older life as it did when you were still a wee one. When we are young we need the HGH—human growth hormone—to grow our bones and [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=arunabhsingh.wordpress.com&amp;blog=256414&amp;post=33&amp;subd=arunabhsingh&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p>HGH—human growth hormoneIt is your pituitary gland that produces the ever so important HGH that your body needs. Unfortunately this gland does not secrete this as much in your older life as it did when you were still a wee one.</p>
<p>When we are young we need the HGH—human growth hormone—to grow our bones and organs etc. and in our adult life this hormone has a big affect on our metabolism rates as well as our immune systems and how well they perform throughout our lives.</p>
<p>Much of the HGH in our bodies is secreted during the time we spend sleeping and it is all due to the fact that the hypothalamus triggers the reaction in our anterior pituitary. It is our tissues, bones and muscles that get the most out of HGH though the rest of the body does benefit as well.</p>
<p>As we age and our bodies produce and secrete less and less human growth hormone we start to feel more tired, we start to look older and just generally feel less well not to mention that fact that we tend to get fatter.</p>
<p>While HGH is one of the hormones that do the body good, there are some that are not quite as helpful all the time. For example insulin. When we eat unhealthy diets filled with refined carbs and sugars the body is gong to go wild with the amount of insulin that it produces leading to adult onset diabetes. This can be deadly if not treated and even when treated is a giant pain in the butt to live with. Insulin is not the only hormone that can wreak havoc on your body though, there is also cortisol. This is the hormone known as the flight or fight hormone. This sucker ruins your tissues, even your brain tissues! That is why sometimes we start to lose our mental functioning, but when you start to take HGH it can reverse these negative effects all over your body.</p>
<p>Human growth hormone is actually called the anti aging hormone by many because of how much it can do for the aging human body.<!-- D(["mb","\u003c/p\&amp;gt;\n\u003cp\&amp;gt;A few of the many benefits that you can see (and feel!) when taking HGH are:\u003c/p\&amp;gt;\n\u003cul\&amp;gt;\u003cli\&amp;gt;Better immune system function\u003c/li\&amp;gt;\u003cli\&amp;gt;Better mental capacity\u003c/li\&amp;gt;\u003cli\&amp;gt;Muscle gain\u003c/li\&amp;gt;\u003cli\&amp;gt;Fat loss\u003c/li\&amp;gt;\u003cli\&amp;gt;Plumped up organs, those that has previously been shrinking with age\u003c/li\&amp;gt;\u003cli\&amp;gt;More energy to do fun stuff\u003c/li\&amp;gt;\n\u003cli\&amp;gt;Better kidney function\u003c/li\&amp;gt;\u003cli\&amp;gt;Lower blood pressure\u003c/li\&amp;gt;\u003cli\&amp;gt;Lower cholesterol\u003c/li\&amp;gt;\u003cli\&amp;gt;Better cardiac function\u003c/li\&amp;gt;\u003cli\&amp;gt;Better bone density\u003c/li\&amp;gt;\u003cli\&amp;gt;Balanced electromagnetic field\u003c/li\&amp;gt;\u003c/ul\&amp;gt;\n\u003cp\&amp;gt;IT is a fact that HGH and IGF-1 can help you manage the aging\nprocess better while keeping you fit and healthy. This happens by\nkeeping the genetic codes in order on all of the different proteins,\nhormones and even the enzymes that you need to keep your cells working\nas they should be. Sure you can take vitamin C and vitamin E as they\nwill help to keep your DNA and in check as well as your immune system\nfunctioning well, but HGH and IGF-1 will make an even bigger\ndifference, in fact they can make all of the difference. These help you\nto have your DNA fixed up before the cells divide. HGH even gets the\nnucleic acids and the amino acids into the various cells and membranes.\nFrom there it is IGF-1 that gets the nucleic acids straight into the\nnucleus of the cell, straight to the heart of the DNA. This is powerful\nand the difference it will have on your body is outstanding.\u003c/p\&amp;gt;\n\u003cp\&amp;gt;HGH is not the only kind of endocrine hormone that is in your body.\u003c/p\&amp;gt;\n\u003cp\&amp;gt;There are many others such as:\u003c/p\&amp;gt;\n\u003cul\&amp;gt;\u003cli\&amp;gt;Estrogen\u003c/li\&amp;gt;\u003cli\&amp;gt;Progesterone\u003c/li\&amp;gt;\u003cli\&amp;gt;Testosterone\u003c/li\&amp;gt;\u003cli\&amp;gt;Melatonin\u003c/li\&amp;gt;\u003cli\&amp;gt;DHEA\u003c/li\&amp;gt;\u003c/ul\&amp;gt;\n\u003cp\&amp;gt;All of these hormones lower in production as we get older and more\nand more patients are turning to hormone replacement therapies to\ncounteract the aging process. And while these others can help you in\nmany ways only HGH can truly help you to prevent the signs and effects\nof aging.\u003c/p\&amp;gt;\n\u003cp\&amp;gt;It is during adolescence and even into your twenties that your HGH\nlevels are the highest. For example most people at around 25 are\nproducing 600 mg of human growth hormone. But by the time you are 60 or\n70 years old you could have as little as 15 percent of that amount!\nThat is a massive difference that affects your body in ways that can\ncripple your life. And the scariest part is that if you are not the\nhealthiest eater you could be down to that 15 percent when you are only\n40! And let&#39;s face it, most of us are far from having a healthy diet\neach day.",1] );  //--></p>
<p>A few of the many benefits that you can see (and feel!) when taking HGH are:</p>
<ul>
<li>Better immune system function</li>
<li>Better mental capacity</li>
<li>Muscle gain</li>
<li>Fat loss</li>
<li>Plumped up organs, those that has previously been shrinking with age</li>
<li>More energy to do fun stuff</li>
<li>Better kidney function</li>
<li>Lower blood pressure</li>
<li>Lower cholesterol</li>
<li>Better cardiac function</li>
<li>Better bone density</li>
<li>Balanced electromagnetic field</li>
</ul>
<p>IT is a fact that HGH and IGF-1 can help you manage the aging process better while keeping you fit and healthy. This happens by keeping the genetic codes in order on all of the different proteins, hormones and even the enzymes that you need to keep your cells working as they should be. Sure you can take vitamin C and vitamin E as they will help to keep your DNA and in check as well as your immune system functioning well, but HGH and IGF-1 will make an even bigger difference, in fact they can make all of the difference. These help you to have your DNA fixed up before the cells divide. HGH even gets the nucleic acids and the amino acids into the various cells and membranes. From there it is IGF-1 that gets the nucleic acids straight into the nucleus of the cell, straight to the heart of the DNA. This is powerful and the difference it will have on your body is outstanding.</p>
<p>HGH is not the only kind of endocrine hormone that is in your body.</p>
<p>There are many others such as:</p>
<ul>
<li>Estrogen</li>
<li>Progesterone</li>
<li>Testosterone</li>
<li>Melatonin</li>
<li>DHEA</li>
</ul>
<p>All of these hormones lower in production as we get older and more and more patients are turning to hormone replacement therapies to counteract the aging process. And while these others can help you in many ways only HGH can truly help you to prevent the signs and effects of aging.</p>
<p>It is during adolescence and even into your twenties that your HGH levels are the highest. For example most people at around 25 are producing 600 mg of human growth hormone. But by the time you are 60 or 70 years old you could have as little as 15 percent of that amount! That is a massive difference that affects your body in ways that can cripple your life. And the scariest part is that if you are not the healthiest eater you could be down to that 15 percent when you are only 40! And let&#8217;s face it, most of us are far from having a healthy diet each day.<!-- D(["mb","\u003c/p\&amp;gt;\n\u003cp\&amp;gt;The simple facts are that once you hit 21 you are losing about 14\npercent of your HGH per decade. You know what this means right? It\nmeans that by the time you are seriously losing out on good health.\u003c/p\&amp;gt;\n\u003cp\&amp;gt;Here it is broken down into simple numerical values:\u003c/p\&amp;gt;\n\u003cp\&amp;gt;Okay, when we are about 20 years old we are cranking out about 500 micrograms of human growth hormone.\u003c/p\&amp;gt;\n\u003cp\&amp;gt;At the age of 40 we are secreting about 200 micrograms.\u003c/p\&amp;gt;\n\u003cp\&amp;gt;Then finally at 80 we are only producing a lowly 25 micrograms.\u003c/p\&amp;gt;\n\u003cp\&amp;gt;That is a serious difference, is it not? Shocking!\u003c/p\&amp;gt;\n\u003cp\&amp;gt;When you are walking down the street and you see those older people\nwho are all weak and mushy looking, those that are fat and who seem to\nhave zero interest in anything at all, those are the people who need a\nlittle pick me up in the form of HGH.\u003c/p\&amp;gt;\n\u003cp\&amp;gt;People who are lacking in their HGH even lose interest in sex and\nthey can have a really hard time keeping track of things in their mind\nbecause their memory is just not what it used to be when they were\nproducing enough HGH each day.\u003c/p\&amp;gt;\n\u003cp\&amp;gt;When you want to see these daily issues disappear then you want to\ntalk to your doctor about HGH injections. You will begin to look better\nfeel better and actually see these signs of aging be reversed.\u003c/p\&amp;gt;\n\u003cp\&amp;gt;And if you really want to live forever—or at least longer than you\nwould have before—then you want to combine HGH treatments with a\nhealthy and well balanced diet. Keeping the calorie down and eating\nplenty of protein is always a good way to go.\u003c/p\&amp;gt;\n\u003cp\&amp;gt;You can have some tests done that are pretty simple. They will\nsimply measure your plasma IGF-1 levels. If you are coming in at under\n350 IU then you are lacking in HGH.\u003c/p\&amp;gt;\n\t\u003c/div\&amp;gt;\n\n\t\n                        \n",0] );  //--></p>
<p>The simple facts are that once you hit 21 you are losing about 14 percent of your HGH per decade. You know what this means right? It means that by the time you are seriously losing out on good health.</p>
<p>Here it is broken down into simple numerical values:</p>
<p>Okay, when we are about 20 years old we are cranking out about 500 micrograms of human growth hormone.</p>
<p>At the age of 40 we are secreting about 200 micrograms.</p>
<p>Then finally at 80 we are only producing a lowly 25 micrograms.</p>
<p>That is a serious difference, is it not? Shocking!</p>
<p>When you are walking down the street and you see those older people who are all weak and mushy looking, those that are fat and who seem to have zero interest in anything at all, those are the people who need a little pick me up in the form of HGH.</p>
<p>People who are lacking in their HGH even lose interest in sex and they can have a really hard time keeping track of things in their mind because their memory is just not what it used to be when they were producing enough HGH each day.</p>
<p>When you want to see these daily issues disappear then you want to talk to your doctor about HGH injections. You will begin to look better feel better and actually see these signs of aging be reversed.</p>
<p>And if you really want to live forever—or at least longer than you would have before—then you want to combine HGH treatments with a healthy and well balanced diet. Keeping the calorie down and eating plenty of protein is always a good way to go.</p>
<p>You can have some tests done that are pretty simple. They will simply measure your plasma IGF-1 levels. If you are coming in at under 350 IU then you are lacking in HGH.</p>
<p>http://www.humanhormones.com/</p>
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		<link>http://arunabhsingh.wordpress.com/2007/03/15/32/</link>
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		<pubDate>Thu, 15 Mar 2007 12:37:41 +0000</pubDate>
		<dc:creator>Arunabh Singh</dc:creator>
				<category><![CDATA[Evolution]]></category>

		<guid isPermaLink="false">http://arunabhsingh.wordpress.com/2007/03/15/32/</guid>
		<description><![CDATA[In the beginning there was only one very small and very simple biological organism. As it evolved, it&#8217;s features diverged. Over the past 3.5 billion years or so, all of the various living organisms we see around us developed from this continuing divergence. Evolution is always working within every species, always changing each species in [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=arunabhsingh.wordpress.com&amp;blog=256414&amp;post=32&amp;subd=arunabhsingh&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p>In the beginning there was only one very small and very simple 				  biological organism. As it evolved, it&#8217;s features diverged. Over the past 3.5 				  billion years or so, all of the various living organisms we see around us 				  developed from this continuing divergence.</p>
<p>Evolution is always working within every species, always 				  changing each species in both form and function. If a desirable mutation should 				  occur in a very large gene pool (such as the human in China) it would be 				  extremely slow to become a standard feature of that gene pool since it must 				  first propagate generation by generation across the entire huge gene pool. A 				  human feature or functional change in China might take hundreds of thousands of 				  years, for example. If a small human gene pool (tribe) should become isolated, 				  by geographical separation perhaps, the pool can change quite rapidly, on the 				  order of a few thousand years. This is how the various human races came to be. 				  If the differentiation continued and the gene pools were not mixed, eventually 				  the different races would become different species. Modern transportation will 				  never allow this to happen, of course.</p>
<p>Homo erectus existed for about 1.9 million years. It was a very 				  successful human species and changed very slowly over that period of time. We 				  don&#8217;t know for sure where the modern human (Homo sapiens sapiens) developed, 				  but it seemed to be quite sudden and happened about 180,000 years ago. It&#8217;s a 				  guess, but perhaps a small Homo erectus tribe became completely isolated under 				  severe environmental conditions, one that caused rapid mutation selection so 				  that the differences between erectus and sapiens occurred in a very short time. 				  Such large scale change in a short time could only occur in a very small gene 				  pool.</p>
<p>The idea of a &#8216;species&#8217; is a human one, an intellectual 				  approximation that we use to help us categorize various forms (organisms) of 				  life. It is also a hazy concept, because every &#8216;species&#8217; we define is actually 				  in transition from one species to another and in most cases there is at least 				  one other organism which is quite similar to the one being categorized, so 				  similar that it is hard to call it a separate species. Even our categorization 				  of the fossil history of man is highly controversial. Who can say exactly when 				  Australopithecus africanus ceased to exist and Homo habilis began? Or were they 				  merely variations in time within the same species?</p>
<p>So, the concept of &#8216;species&#8217; is archaic. We thought that the 				  forms of life were stable and that they could be categorized in a fixed 				  fashion. We find, instead, that what we now see as the current set of &#8216;species&#8217; 				  around us is actually a current snapshot and that all of these &#8216;species&#8217; are in 				  transition.</p>
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		<title>The Evolution Process</title>
		<link>http://arunabhsingh.wordpress.com/2007/03/15/the-evolution-process-2/</link>
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		<pubDate>Thu, 15 Mar 2007 12:34:58 +0000</pubDate>
		<dc:creator>Arunabh Singh</dc:creator>
				<category><![CDATA[Evolution]]></category>

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		<description><![CDATA[Evolution is the change with time of the gene pool of a species. The mechanisms of evolution are mutation, natural selection, recombination and gene flow. Mutation provides all initial change. A mutation occurs when the DNA does not replicate perfectly. When a mutation occurs, a new allele is created. As a first approximation, these accidents [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=arunabhsingh.wordpress.com&amp;blog=256414&amp;post=29&amp;subd=arunabhsingh&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p>Evolution is the change with time of the gene pool of a species. 				  The mechanisms of evolution are <strong><em>mutation</em></strong>, <strong><em>natural 				  selection</em></strong>, <strong><em>recombination</em></strong> and <strong><em>gene flow</em></strong>.</p>
<p><strong><em>Mutation</em></strong> provides all initial change. A mutation 				  occurs when the DNA does not replicate perfectly. When a mutation occurs, a new 				  allele is created. As a first approximation, these accidents (mutations) are 				  random (can occur at any location along the DNA). The rate of these accidents 				  is relatively constant within a given species. If the accident occurs in a 				  critical location (believed to be less than 10% of the total in man), the 				  result is usually disastrous. Other areas will accept change with no immediate 				  consequence. Once made, the mutation is perpetuated and variability within the 				  gene pool of the species is increased. Mutations add variability to the gene 				  pool.</p>
<p><strong><em>Natural selection</em></strong> occurs when the viability of an 				  allele is tested in real life. It makes only one test. Contrary to popular 				  opinion, evolution does not select the fittest, strongest, or most superior 				  organism. It is instead a question of how many offspring the organism will have 				  which in turn will reach sufficient maturity to have its own offspring. If the 				  effect is positive, the allele will become a permanent part of the gene pool. 				  If the effect is very successful, it will quickly become a dominant allele. If 				  the effect is neutral or negative, the allele will not spread rapidly through 				  the gene pool and, usually, will disappear from the gene pool. If more than one 				  mutation is being tested at the same time, usually the case, then it is the 				  summed effect tested. Not all good mutations make it. Some mutations would be 				  good at one time and bad at another, depending on the environment then. A 				  mutation that was necessary at one time may become unnecessary at another time 				  and be consequently negated. Most of the time, the alleles removed or negated 				  are those that harm the organism in that environment. Natural selection removes 				  variability from the gene pool.</p>
<p>The environment which an organism faces and must survive is a 				  complex one, one which is more than climate and food supply, although those are 				  the essential elements that serve as a starting point in the study of 				  evolution.</p>
<p>First of all, the mutation process is not altogether random. An 				  intricate process called recombination developed early in sexual animals. This 				  process serves to mix the alleles available in the two parental gene sets to 				  provide more variability against the environment. It also results in many 				  reproduction errors (mutations). Repair functions were developed by evolution 				  for DNA errors to offset this error propensity. Since both the dissection means 				  and the repair means are relatively fixed processes, then both the dissection 				  errors and the errors in repair will follow certain patterns. When these 				  coincide, a new allele is formed. Mutations, then, occur in clusters around 				  particular loci not yet known or cataloged. Certain defects occur, therefore, 				  with a given frequency, which are wholly the result of the process and not the 				  assumption of a defective ancestral gene.</p>
<p>Another factor which enters into genetic change is that the 				  product of a purely random process (and a large part of human mutations fit 				  that description) will drift to one side or another until an outside force 				  interferes with the drift. For example, the human is now growing larger. If 				  this is the result of genetic drift, it will continue until some other process 				  interferes, such as a shortage of food.</p>
<p>Most of the struggle in life is the struggle for enough food to 				  avoid starvation and an ability to survive the climate. This was the entire 				  struggle at the beginning, but as life became more complex, the selection 				  process also became more complex. Once life began, however, other life became a 				  part of its environment. The food chains were started.</p>
<p>The basic element of species survival is the ability of the 				  individual to survive long enough to insure the survival of its offspring to 				  the point when they also have offspring. If the offspring require no care, then 				  the immediate death of the parent is of no consequence. In the case of the 				  higher animals, those which require care during their maturation, the life of 				  the caring parent must extend through that maturation period (and, of course, 				  the parent must perform its function properly).</p>
<p>If an animal must endure an environment in which its population 				  is normally controlled by predators, it is usual that the young suffer a higher 				  death rate than the adults. In such cases the parents will usually live through 				  several breeding seasons, to offset losses of their young. Some animals resort 				  to large numbers of offspring, thereby feeding the predators, with enough left 				  over to continue the species.</p>
<p>As animals became more complex, they themselves began to be an 				  appreciable part of their own selection (survival) environment. Herein lies the 				  most complex of all genetic processes, and examples abound. Sexual selection 				  (based on an appearance which is sexually attractive) is probably (not for 				  sure) the most common of these. There are times when sexual selection actually 				  harms the ability of the species to survive. There are thousands of examples, 				  but to select one, consider the Cardinal, a beautiful small bird that is quite 				  common in North America. Somewhere back in time, the drab little hens, who had 				  drab little roosters as soul-mates, took a liking to the color red and began 				  choosing mates based on a hint of red in their feathers. Since they mated with 				  roosters who had red in their makeup, their offspring tended to have red in 				  their feathers, which suited the next generation of hens just fine. Quite 				  quickly the rooster was a bright red, and the best target in the world for a 				  predator. The predator, usually a hawk, could lock on to that bright red target 				  and have a meal in no time. As a result the Cardinal rooster is quite skittish, 				  and he should be, but without the red there is no sex and his genes end.</p>
<p><strong><em>Recombination</em></strong> occurs in sexually reproducing 				  organisms, such as the human. The parent has two sets of chromosomes in each 				  cell, one from its father, the other from its mother. The sperm and the egg 				  carry only one set in each. The one set carried by the sperm or egg is not a 				  whole set from either grandparent but is a mixture of the two. Both original 				  sets of chromosomes, in the case of each parent, are dissected and scrambled, 				  then reformed with entirely new combinations of alleles from both grandparents. 				  This process adds variability to the offspring and allows testing of new allele 				  combinations. Recombination allows new combinations of the variability in the 				  gene pool</p>
<p><strong><em>Gene flow</em></strong> occurs when populations of a species 				  that have been separated are united and the differing sets of alleles in each 				  gene pool flow into the gene pool of the other. Our species, suddenly reunited 				  with widespread transportation, is an excellent example of this effect. Gene 				  flow distributes the variability in the gene pool.</p>
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		<link>http://arunabhsingh.wordpress.com/2007/03/15/31/</link>
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		<pubDate>Thu, 15 Mar 2007 12:34:40 +0000</pubDate>
		<dc:creator>Arunabh Singh</dc:creator>
				<category><![CDATA[Evolution]]></category>

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		<description><![CDATA[Life is a fact in the universe. Life exists. It exists within the same rules in the universe that everything else must follow. Evolution is a reactive process. Evolution is a requirement of life. The life produced by evolution is a part of the universe, as is a galaxy and a grain of sand. Evolution [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=arunabhsingh.wordpress.com&amp;blog=256414&amp;post=31&amp;subd=arunabhsingh&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p>Life is a fact in the universe. Life exists. It exists within 				  the same rules in the universe that everything else must follow. Evolution is a 				  reactive process. Evolution is a requirement of life. The life produced by 				  evolution is a part of the universe, as is a galaxy and a grain of sand. 				  Evolution has no compassion and it has no goals. A given strain of life, while 				  undergoing evolution and enduring a given environment, either survives or does 				  not. The survival of a species rests on the sum total of the individual actions 				  of each member within that species. Action by any member of a species, which is 				  contrary to the survival of that species, is perverse (contrary to nature).</p>
<p>Evolution is obviously no friend of man or his culture. It 				  brought us here, then dumped the whole problem on us. Through sex it has a 				  hammerlock on us that will be painful no matter what we do. It appears that we 				  either return to the tooth and claw so that nature can cleanse and maintain our 				  gene pool, or watch ourselves sink back to the status of the beginning man. The 				  first would allow us to retain our stature at the cost of losing our humanity. 				  The latter is slower, but we lose both our stature and our humanity. Each 				  choice is equally unacceptable. One thing is clear: Slow degeneration is the 				  default condition.</p>
<p>A big hope for the far future lies in the genome project. In 				  time we can clean up our genome, streamline it down to size, and then maintain 				  it free of defects. This would take care of our problems with evolution but it 				  might be way far in the future. Many will say that this is an impossible job. 				  The amount of technical work, alone, is staggering. The mechanics of cleaning 				  up the genome of all humankind all over the world appears impossible. 				  Pre-conception examinations of the haploid DNA may be a possibility and it 				  would fit in with a need for centralized genetic control. This may also turn 				  out to be an impossible job. The only recourse then will be to start a process 				  by which a new super-DNA structure is introduced into the population on a 				  scheduled basis, one that will not mix, thus starting a new species to replace 				  our own. Either technique will provide a great challenge to overcome fears and 				  objections.</p>
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		<title>The Evolution Process</title>
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		<pubDate>Thu, 15 Mar 2007 12:34:02 +0000</pubDate>
		<dc:creator>Arunabh Singh</dc:creator>
				<category><![CDATA[Evolution]]></category>

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		<description><![CDATA[Evolution is the change with time of the gene pool of a species. The mechanisms of evolution are mutation, natural selection, recombination and gene flow. Mutation provides all initial change. A mutation occurs when the DNA does not replicate perfectly. When a mutation occurs, a new allele is created. As a first approximation, these accidents [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=arunabhsingh.wordpress.com&amp;blog=256414&amp;post=30&amp;subd=arunabhsingh&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p>Evolution is the change with time of the gene pool of a species. 				  The mechanisms of evolution are <strong><em>mutation</em></strong>, <strong><em>natural 				  selection</em></strong>, <strong><em>recombination</em></strong> and <strong><em>gene flow</em></strong>.</p>
<p><strong><em>Mutation</em></strong> provides all initial change. A mutation 				  occurs when the DNA does not replicate perfectly. When a mutation occurs, a new 				  allele is created. As a first approximation, these accidents (mutations) are 				  random (can occur at any location along the DNA). The rate of these accidents 				  is relatively constant within a given species. If the accident occurs in a 				  critical location (believed to be less than 10% of the total in man), the 				  result is usually disastrous. Other areas will accept change with no immediate 				  consequence. Once made, the mutation is perpetuated and variability within the 				  gene pool of the species is increased. Mutations add variability to the gene 				  pool.</p>
<p><strong><em>Natural selection</em></strong> occurs when the viability of an 				  allele is tested in real life. It makes only one test. Contrary to popular 				  opinion, evolution does not select the fittest, strongest, or most superior 				  organism. It is instead a question of how many offspring the organism will have 				  which in turn will reach sufficient maturity to have its own offspring. If the 				  effect is positive, the allele will become a permanent part of the gene pool. 				  If the effect is very successful, it will quickly become a dominant allele. If 				  the effect is neutral or negative, the allele will not spread rapidly through 				  the gene pool and, usually, will disappear from the gene pool. If more than one 				  mutation is being tested at the same time, usually the case, then it is the 				  summed effect tested. Not all good mutations make it. Some mutations would be 				  good at one time and bad at another, depending on the environment then. A 				  mutation that was necessary at one time may become unnecessary at another time 				  and be consequently negated. Most of the time, the alleles removed or negated 				  are those that harm the organism in that environment. Natural selection removes 				  variability from the gene pool.</p>
<p>The environment which an organism faces and must survive is a 				  complex one, one which is more than climate and food supply, although those are 				  the essential elements that serve as a starting point in the study of 				  evolution.</p>
<p>First of all, the mutation process is not altogether random. An 				  intricate process called recombination developed early in sexual animals. This 				  process serves to mix the alleles available in the two parental gene sets to 				  provide more variability against the environment. It also results in many 				  reproduction errors (mutations). Repair functions were developed by evolution 				  for DNA errors to offset this error propensity. Since both the dissection means 				  and the repair means are relatively fixed processes, then both the dissection 				  errors and the errors in repair will follow certain patterns. When these 				  coincide, a new allele is formed. Mutations, then, occur in clusters around 				  particular loci not yet known or cataloged. Certain defects occur, therefore, 				  with a given frequency, which are wholly the result of the process and not the 				  assumption of a defective ancestral gene.</p>
<p>Another factor which enters into genetic change is that the 				  product of a purely random process (and a large part of human mutations fit 				  that description) will drift to one side or another until an outside force 				  interferes with the drift. For example, the human is now growing larger. If 				  this is the result of genetic drift, it will continue until some other process 				  interferes, such as a shortage of food.</p>
<p>Most of the struggle in life is the struggle for enough food to 				  avoid starvation and an ability to survive the climate. This was the entire 				  struggle at the beginning, but as life became more complex, the selection 				  process also became more complex. Once life began, however, other life became a 				  part of its environment. The food chains were started.</p>
<p>The basic element of species survival is the ability of the 				  individual to survive long enough to insure the survival of its offspring to 				  the point when they also have offspring. If the offspring require no care, then 				  the immediate death of the parent is of no consequence. In the case of the 				  higher animals, those which require care during their maturation, the life of 				  the caring parent must extend through that maturation period (and, of course, 				  the parent must perform its function properly).</p>
<p>If an animal must endure an environment in which its population 				  is normally controlled by predators, it is usual that the young suffer a higher 				  death rate than the adults. In such cases the parents will usually live through 				  several breeding seasons, to offset losses of their young. Some animals resort 				  to large numbers of offspring, thereby feeding the predators, with enough left 				  over to continue the species.</p>
<p>As animals became more complex, they themselves began to be an 				  appreciable part of their own selection (survival) environment. Herein lies the 				  most complex of all genetic processes, and examples abound. Sexual selection 				  (based on an appearance which is sexually attractive) is probably (not for 				  sure) the most common of these. There are times when sexual selection actually 				  harms the ability of the species to survive. There are thousands of examples, 				  but to select one, consider the Cardinal, a beautiful small bird that is quite 				  common in North America. Somewhere back in time, the drab little hens, who had 				  drab little roosters as soul-mates, took a liking to the color red and began 				  choosing mates based on a hint of red in their feathers. Since they mated with 				  roosters who had red in their makeup, their offspring tended to have red in 				  their feathers, which suited the next generation of hens just fine. Quite 				  quickly the rooster was a bright red, and the best target in the world for a 				  predator. The predator, usually a hawk, could lock on to that bright red target 				  and have a meal in no time. As a result the Cardinal rooster is quite skittish, 				  and he should be, but without the red there is no sex and his genes end.</p>
<p><strong><em>Recombination</em></strong> occurs in sexually reproducing 				  organisms, such as the human. The parent has two sets of chromosomes in each 				  cell, one from its father, the other from its mother. The sperm and the egg 				  carry only one set in each. The one set carried by the sperm or egg is not a 				  whole set from either grandparent but is a mixture of the two. Both original 				  sets of chromosomes, in the case of each parent, are dissected and scrambled, 				  then reformed with entirely new combinations of alleles from both grandparents. 				  This process adds variability to the offspring and allows testing of new allele 				  combinations. Recombination allows new combinations of the variability in the 				  gene pool</p>
<p><strong><em>Gene flow</em></strong> occurs when populations of a species 				  that have been separated are united and the differing sets of alleles in each 				  gene pool flow into the gene pool of the other. Our species, suddenly reunited 				  with widespread transportation, is an excellent example of this effect. Gene 				  flow distributes the variability in the gene pool.</p>
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		<title>The Genome is a Digital Program.</title>
		<link>http://arunabhsingh.wordpress.com/2007/03/15/the-genome-is-a-digital-program/</link>
		<comments>http://arunabhsingh.wordpress.com/2007/03/15/the-genome-is-a-digital-program/#comments</comments>
		<pubDate>Thu, 15 Mar 2007 12:33:26 +0000</pubDate>
		<dc:creator>Arunabh Singh</dc:creator>
				<category><![CDATA[Evolution]]></category>

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		<description><![CDATA[When executed, it produces a human. This section is repeated in Man, the Digital Machine. It is included here for continuity of thought. The DNA which describes each individual is in a digital code. The code is made up of four possible values. In number form, these could be expressed as 0, 1, 2, 3, [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=arunabhsingh.wordpress.com&amp;blog=256414&amp;post=28&amp;subd=arunabhsingh&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p><strong>When executed, it produces a human. </strong></p>
<p><em>This section is repeated in </em><a href="http://www.onelife.com/evolve/digman.html"><font color="#0000ff">Man, the Digital Machine.</font></a> <em>It is included here for 				  continuity of thought.</em></p>
<p>The DNA which describes each individual is in a digital code. 				  The code is made up of four possible values. In number form, these could be 				  expressed as 0, 1, 2, 3, but are normally expressed as four letter values:<strong> 				  A, C, G, and T</strong>. These are always paired with their reciprocal value (see 				  the text OneLife for more detail). <strong>Note that the DNA description of all 				  living things is made up of only four basic construction blocks.</strong> There are 				  about three billion of these <strong>base pairs</strong> in the human genome. These are 				  used in groups of three, called <strong>codons</strong>. Each codon consists of three 				  base pairs, each of which may carry one of four possible values. The number of 				  codon values which can be expressed in three elements of four values each is 				  64. Normally these values would be assigned as 0, 1, 2, etc. through the number 				  63. Instead, all possible codons are expressed in the following table:</p>
<p align="center">
<table border="1" cellpadding="3" cellspacing="3" width="450">
<tr>
<td align="center">AAA</td>
<td align="center">AAC</td>
<td align="center">AAG</td>
<td align="center">AAT</td>
<td align="center">ACA</td>
<td align="center">ACC</td>
<td align="center">ACG</td>
<td align="center">ACT</td>
</tr>
<tr>
<td align="center">AGA</td>
<td align="center">AGC</td>
<td align="center">AGG</td>
<td align="center">AGT</td>
<td align="center">ATA</td>
<td align="center">ATC</td>
<td align="center">ATG</td>
<td align="center">ATT</td>
</tr>
<tr>
<td align="center">CAA</td>
<td align="center">CAC</td>
<td align="center">CAG</td>
<td align="center">CAT</td>
<td align="center">CCA</td>
<td align="center">CCC</td>
<td align="center">CCG</td>
<td align="center">CCT</td>
</tr>
<tr>
<td align="center">CGA</td>
<td align="center">CGC</td>
<td align="center">CGG</td>
<td align="center">CGT</td>
<td align="center">CTA</td>
<td align="center">CTC</td>
<td align="center">CTG</td>
<td align="center">CTT</td>
</tr>
<tr>
<td align="center">GAA</td>
<td align="center">GAC</td>
<td align="center">GAG</td>
<td align="center">GAT</td>
<td align="center">GCA</td>
<td align="center">GCC</td>
<td align="center">GCG</td>
<td align="center">GCT</td>
</tr>
<tr>
<td align="center">GGA</td>
<td align="center">GGC</td>
<td align="center">GGG</td>
<td align="center">GGT</td>
<td align="center">GTA</td>
<td align="center">GTC</td>
<td align="center">GTG</td>
<td align="center">GTT</td>
</tr>
<tr>
<td align="center">TAA</td>
<td align="center">TAC</td>
<td align="center">TAG</td>
<td align="center">TAT</td>
<td align="center">TCA</td>
<td align="center">TCC</td>
<td align="center">TCG</td>
<td align="center">TCT</td>
</tr>
<tr>
<td align="center">TGA</td>
<td align="center">TGC</td>
<td align="center">TGG</td>
<td align="center">TGT</td>
<td align="center">TTA</td>
<td align="center">TTC</td>
<td align="center">TTG</td>
<td align="center">TTT</td>
</tr>
</table>
<p>Note that this list contains all of the possible codons, there 				  are no CAA.5 or CTT 1/2 codons. The beauty of things digital is the simplicity 				  and precision. There are 64 precise arrangements of base pairs and only 64. 				  <strong>All life is constructed in response to these precise codon values, and no 				  other. </strong></p>
<p>Most of these sixty-four combinations are used to produce 20 				  protein building blocks, called <strong>amino acids</strong>, from which the human 				  organism is constructed. Some of the others are duplicates, and some are called 				  &#8220;stop&#8221; codes. The following list shows the correspondence between the codon 				  values and the 20 amino acids which in man will be produced from that 				  coding:</p>
<p align="center">
<table border="1" cellpadding="2" width="450">
<tr>
<th align="left" nowrap="NOWRAP">Amino Acid</th>
<th colspan="6" align="left">Codons which code for that 							 amino acid</th>
</tr>
<tr>
<th align="left" nowrap="NOWRAP">Alenine</th>
<td>GCA</td>
<td>GCC</td>
<td>GCG</td>
<td>GCT</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
</tr>
<tr>
<th align="left" nowrap="NOWRAP">Cysteine</th>
<td>TGC</td>
<td>TGT</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
</tr>
<tr>
<th align="left" nowrap="NOWRAP">Aspartic acid</th>
<td>GAC</td>
<td>GAT</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
</tr>
<tr>
<th align="left" nowrap="NOWRAP">Glutamic acid</th>
<td>GAA</td>
<td>GAG</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
</tr>
<tr>
<th align="left" nowrap="NOWRAP">Phenylalanine</th>
<td>TTC</td>
<td>TTT</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
</tr>
<tr>
<th align="left" nowrap="NOWRAP">Glycine</th>
<td>GGA</td>
<td>GGC</td>
<td>GGG</td>
<td>GGT</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
</tr>
<tr>
<th align="left" nowrap="NOWRAP">Histidine</th>
<td>CAC</td>
<td>CAT</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
</tr>
<tr>
<th align="left" nowrap="NOWRAP">Isoleucine</th>
<td>ATA</td>
<td>ATC</td>
<td>ATT</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
</tr>
<tr>
<th align="left" nowrap="NOWRAP">Lysine</th>
<td>AAA</td>
<td>AAG</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
</tr>
<tr>
<th align="left" nowrap="NOWRAP">Leucine</th>
<td>TTA</td>
<td>TTG</td>
<td>CTA</td>
<td>CTC</td>
<td>CTG</td>
<td>CTT</td>
</tr>
<tr>
<th align="left" nowrap="NOWRAP">Methionine</th>
<td>ATG</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
</tr>
<tr>
<th align="left" nowrap="NOWRAP">Asparagine</th>
<td>AAC</td>
<td>AAT</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
</tr>
<tr>
<th align="left" nowrap="NOWRAP">Proline</th>
<td>CCA</td>
<td>CCC</td>
<td>CCG</td>
<td>CCT</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
</tr>
<tr>
<th align="left" nowrap="NOWRAP">Glutamine</th>
<td>CAA</td>
<td>CAG</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
</tr>
<tr>
<th align="left" nowrap="NOWRAP">Arginine</th>
<td>AGA</td>
<td>AGG</td>
<td>CGA</td>
<td>CGC</td>
<td>CGG</td>
<td>CGT</td>
</tr>
<tr>
<th align="left" nowrap="NOWRAP">Serine</th>
<td>AGC</td>
<td>AGT</td>
<td>TCA</td>
<td>TCC</td>
<td>TCG</td>
<td>TCT</td>
</tr>
<tr>
<th align="left" nowrap="NOWRAP">Theonine</th>
<td>ACA</td>
<td>ACC</td>
<td>ACG</td>
<td>ACT</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
</tr>
<tr>
<th align="left" nowrap="NOWRAP">Valine</th>
<td>GTA</td>
<td>GTC</td>
<td>GTG</td>
<td>GTT</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
</tr>
<tr>
<th align="left" nowrap="NOWRAP">Tryptophan</th>
<td>TGG</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
</tr>
<tr>
<th align="left" nowrap="NOWRAP">Tyrosine</th>
<td>TAC</td>
<td>TAT</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
<td>&nbsp;</td>
</tr>
</table>
<p>The substance of the human body is constructed from proteins, 				  which in turn are constructed from these 20 amino acids.</p>
<p>As the program in the genome is read codon by codon from a 				  starting code to a codon stop code, the sequence of codons dictate the 				  construction of a protein. A particular series of codons will describe a 				  particular protein which the cell can produce. Such a sequence is called a 				  <strong><em>gene</em></strong>. In the case of man, more than 80,000 different proteins are 				  manufactured in the cells from these digital formulas to form and maintain the 				  overall organism. Some of these proteins are quite complex. The final assembly 				  may total many thousands of various amino acids, all arranged precisely. The 				  genome, then, is a precise digital formula which describes the construction of 				  an entire human being. These instructions include precise formulas for the 				  material used to build the body and precise assembly instructions as well.</p>
<p>Modern computers use binary arithmetic, where each position 				  (bit) has a value of 0 or 1. Since larger numbers are needed, a handier concept 				  is a byte, consisting of eight bits and capable of a value from 0 to 255. The 				  codon set can be represented by assigning values from 0 to 63 and so fits well 				  within a byte. The three billion byte genome representation will fit in any 				  hard disk of 3 gigabytes are more, well within the size range of modern 				  desk-top computers. This is the data base which describes man in such detail 				  that it can actually construct an entire human including all of the 				  instructions for his development and demise. This is the raw data from which 				  knowledge may be obtained. Every particle of man is described in precise 				  detail. Since his instinct detail is also fixed by this coding, that will also 				  be analyzed and cataloged. Since man is driven by his instinct in all social 				  actions, the initial propensity for a particular set of social drives is 				  inherent in his DNA coding and so may be uncovered individual by 				  individual.</p>
<p>The gene is the primary carrier of inherited characteristics. 				  The gene that controls a certain characteristic has a particular physical 				  location in the genome. Due to past mutations, many genes will have structural 				  variability within the population of a species. When two genes have the same 				  purpose (for example eye color) but differ in physical construction (same 				  example blue and brown), they are called alleles. A gene may have many alleles 				  within a given species. The total of all of the genes in the population, 				  including their alleles, is called the <strong><em>gene pool</em></strong> of that species.</p>
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		<title>DNA and Replication</title>
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		<pubDate>Thu, 15 Mar 2007 12:32:45 +0000</pubDate>
		<dc:creator>Arunabh Singh</dc:creator>
				<category><![CDATA[Evolution]]></category>

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		<description><![CDATA[About 100 billion copies of our DNA are distributed throughout our body. Each copy is alive (it can reproduce itself) and is identical to every other copy. DNA has many functions within the life-form. Without DNA, we could not be born. We could not live. We could not grow. Nothing in our body would function. [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=arunabhsingh.wordpress.com&amp;blog=256414&amp;post=27&amp;subd=arunabhsingh&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p>About 100 billion copies of our <strong>DNA</strong> are distributed 				  throughout our body. Each copy is alive (it can reproduce itself) and is 				  identical to every other copy. <strong>DNA</strong> has many functions within the 				  life-form. Without <strong>DNA</strong>, we could not be born. We could not live. We 				  could not grow. Nothing in our body would function. We could not reproduce. In 				  fact, our body could not form. It controls our growth and development from 				  conception. It determines our appearance (size, weight, color of eyes, skin 				  texture, etc.). Indirectly it controls all of our bodily and mental functions 				  (since it details the physical and operating characteristics of all of our 				  components). It even to some extent controls our length of life. <strong>DNA</strong> 				  functions in all life-forms in the same way.</p>
<p>No other tissue in our body is alive. None can reproduce without 				  <strong>DNA</strong>. All tissue other than <strong>DNA</strong> is built in response to action 				  taken by <strong>DNA</strong> and its only purpose is to serve the needs of the 				  <strong>DNA</strong>. <strong>DNA</strong> performs functions necessary for its own survival. It 				  performs functions necessary for our survival. It reproduces itself. It 				  performs functions that allow us to reproduce. Even in our own reproduction, it 				  is our <strong>DNA</strong> that is reproducing. <strong>DNA</strong> works in the same way in all 				  other life-forms. Of the entire body of any life-form, whether plant or animal, 				  the parts of its body that bring life to its existence are the <strong>DNA</strong> in 				  each cell in its body. Life is distributed throughout the body of every living 				  thing.</p>
<p><strong>DNA</strong> has a code that is quite similar in construction to 				  that used in modern digital computers. The code used in computers is called 				  binary and consists of two numbers: 0 and 1. These numbers are then combined to 				  specify entities needed by humans: 0001 becomes the binary equivalent of our 				  number 1, 1111 is the binary equivalent of our number 15, and 01010001 is the 				  binary equivalent of the capital letter Q. Although the computer works in 				  binary, its output to us is then converted to our language so that we can 				  understand it. <strong>DNA</strong> encodes with a slightly more complex system. Unlike 				  the computer that uses 0 and 1, and unlike humans that use a decimal system 0 				  through 9, <strong>DNA </strong>uses a system of four conditions. This system could be 				  symbolized as 0, 1, 2, and 3, but is not normally done so. Instead, <strong>DNA</strong> 				  may be visualized as a code made up of four conditions: <strong>A, T, C,</strong> and 				  <strong>G.</strong> These are called bases and they may appear along the length of the 				  <strong>DNA</strong> in any order. These bases are complex organic molecules that provide 				  the fundamental genetic building blocks for the description of the overall 				  organism that the <strong>DNA</strong> will construct and maintain.</p>
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<td align="center"><img src="http://www.onelife.com/evolve/zba10.gif" height="31" width="32" /> 						is a molecule of adenine.</td>
<td align="center"><img src="http://www.onelife.com/evolve/zbac10.gif" height="31" width="32" /> is a molecule of cytosine.</td>
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<td align="center"><img src="http://www.onelife.com/evolve/zbg10.gif" height="31" width="32" /> 						is a molecule of guanine.</td>
<td align="center"><img src="http://www.onelife.com/evolve/zbat10.gif" height="31" width="32" /> is a molecule of thymine.</td>
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<td colspan="2" align="center"><img src="http://www.onelife.com/evolve/zbaschem.gif" height="227" hspace="100" width="247" /></td>
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<p>The upper and lower red lines indicate the sugar-phosphate 				  &#8220;glue&#8221; that holds the sequence of <strong>bases</strong> together. Between these two 				  &#8220;rails&#8221; are shown four <strong>bases</strong> in schematic form. The two vertical 				  <strong>base</strong> combinations are called <strong>base pairs</strong> and are joined with 				  hydrogen bonds. Note that the <strong>base pairs</strong> are not joined with adjacent 				  pairs except through the common rails. In physical form,<strong> DNA</strong> consists of 				  two strings of bases in the form of a ladder with <strong>base pairs</strong> forming 				  each rung. The ladder is then twisted to form a helix. Each rung of the ladder 				  is constructed of only four possible combinations of <strong>base pairs</strong>. Two of 				  these are shown. The other two are obtained by inverting those shown. <strong>A</strong> 				  will only pair with <strong>T</strong> and <strong>C</strong> will only pair with <strong>G</strong>. The 				  four possible conditions for any rung on the <strong>DNA</strong> ladder are <strong>AT, TA, 				  CG</strong>, and <strong>GC. </strong></p>
<p>To describe an organism, these bases are coded into a long 				  string of <strong>DNA</strong>. This <strong>DNA</strong> coded string must be quite long. The 				  human description is about 3 billion <strong>base pairs</strong> long and consists of 				  24<strong> DNA</strong> strings, called <strong>chromosomes.</strong> The overall genetic material 				  that describes any organism is called its <strong>genome</strong>. The genetic material 				  in each human consists of 2 sets of 23 <strong>chromosomes </strong>in each of about 10 				  billion cells in the body.</p>
<p>The top row in the figure below provides a code for making the 				  substances used in the organism. The lower row of the pair contains the same 				  genetic information, but its code is the reciprocal of the code in the upper 				  row. Wherever a <strong>T</strong> appears in the top row, its reciprocal <strong>A</strong> 				  appears in the lower. <strong>AT</strong>, <strong>CG</strong> and <strong>GC</strong> are the other 				  possibilities.</p>
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<td>DNA strand prior to replication:</td>
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<td><img src="http://www.onelife.com/new-3.gif" height="39" width="459" /></td>
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<td><img src="http://www.onelife.com/new-2.gif" height="141" width="546" /></td>
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<td>&nbsp;</td>
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<td><img src="http://www.onelife.com/new-3.gif" height="39" width="459" /></td>
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<td>2 DNA strands after replication:</td>
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<td><img src="http://www.onelife.com/new-3.gif" height="39" width="459" /></td>
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<p><strong>DNA</strong> reproduces by division. The top two rows in the above 				  figure show a fragment of <strong>DNA </strong>before it starts to reproduce. When the 				  <strong>DNA</strong> replicates, it is immersed in a soup of bases from which it will 				  select the &#8220;food&#8221; that it needs as it grows. Other &#8220;helper&#8221; chemicals are also 				  present. The <strong>DNA</strong> unzips on one end. The zipper moves down the strand at 				  a steady pace. Behind the zipper, the two strands are separated. Unattached<strong> 				  bases</strong> are floating on all sides. One by one, the proper complementary 				  <strong>base</strong> is selected and attached to the free-floating half-strand. When the 				  zipper has completely separated the two halves of the original strand of 				  <strong>DNA</strong> and the two halves have completely filled their new complementary 				  halves, the process is complete. The two separate but identical <strong>DNA</strong> 				  strands result.</p>
<p><strong>DNA</strong> coding resembles computer binary coding in another 				  way. Early personal computers used a series of binary numbers that were eight 				  positions long, such as 11001110 or 00011101. This was termed an eight bit wide 				  word. An eight bit word can encode all of the letters of the alphabet, for use 				  in a word processor, for example, or it can provide numbers from 0 to 255 for 				  use in computation. Modern personal computers are much more versatile, using 				  word lengths of 32 or even 64 bits in length. Another common coding system is 				  used in our written language. It uses 26 possible conditions (a&#8230;z) and 				  variable word lengths to provide a written symbol (code) for every spoken 				  word.<strong> DNA</strong> uses a much simpler system, which is only three positions 				  wide, called <strong>codons.</strong> <strong>ATC</strong>, <strong>TCG</strong>, and <strong>TTT</strong> would be 				  examples of individual <strong>codons.</strong> Since a word length has three possible 				  positions and four possible conditions in each position, sixty-four possible 				  combinations are possible. Not all these combinations (<strong>codons</strong>) provide 				  unique functions. <strong>DNA codons</strong> specify the construction of 20 possible 				  <strong>amino acids</strong>. These<strong> amino acids</strong> may be further combined to form 				  more than 100,000 substances to be used in cell construction and maintenance 				  (in turn building and maintaining the host organism).</p>
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		<pubDate>Thu, 15 Mar 2007 12:31:25 +0000</pubDate>
		<dc:creator>Arunabh Singh</dc:creator>
				<category><![CDATA[Evolution]]></category>

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		<description><![CDATA[Evolution is known fact. It can be demonstrated. No reasonable person can dispute it. Evolution is by far the most important natural process to the human. His very thought and structure came from this process. No human can properly assess his own position in the universe without knowledge of the evolutionary process. Evolution developed the [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=arunabhsingh.wordpress.com&amp;blog=256414&amp;post=26&amp;subd=arunabhsingh&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p><strong><em>Evolution is known fact. It can be demonstrated. No 				  reasonable person can dispute it. Evolution is by far the most important 				  natural process to the human. His very thought and structure came from this 				  process. No human can properly assess his own position in the universe without 				  knowledge of the evolutionary process. Evolution developed the modern human 				  species, and so has a bright side. Evolution also has a dark side. The future 				  of the species depends on knowledge about evolution becoming widespread.</em></strong></p>
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<td colspan="2"><strong><em>There are three forces in opposition 							 to real knowledge about evolution: </em></strong></td>
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<td width="30">&nbsp;</td>
<td><strong>1. Religious rejection</strong> &#8211; A large part of the 							 public view certain knowledge as being anti-God. The study of evolution is an 							 example. These reject the information contained in this text, rather than 							 embrace real knowledge about the real world. They prefer dogma over fact and 							 faith over reason and logic.<br />
This group not only practices evangelism to 							 spread their beliefs, they are militant in their support of those beliefs. As a 							 result, they not only deny provable and measurable fact in favor of dogma, they 							 will also deny any philosophy derived therefrom, even though it may parallel 							 their own.</td>
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<td valign="top" width="30">&nbsp;</td>
<td valign="top"><strong>2. Academic protection of the campus 							 elitist ideology</strong> &#8211; the academic professionals truncate and distort 							 scientific knowledge in order to further political aims toward an egalitarian 							 (socialist) society. They call it &#8216;humanizing&#8217; science. This is intellectual 							 hypocrisy at its worst. Politically correct knowledge is the result.<br />
This 							 group is not only far more righteous than the religious in support of their 							 dogma, it is also more militant in defending it. Whereas the religious will 							 seek conversion within the free will of the convert, socialist ideologues will 							 use any measure to force their dogma on the public.</td>
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<td width="30">&nbsp;</td>
<td><strong>3. Public apathy</strong> &#8211; The conflict between the 							 forces described above leaves a majority of the public confused. As a result, a 							 large percentage does not care. The future of mankind does not concern them. 							 These seek instant self-gratification. As long as they can satisfy their own 							 drives, they are content.<br />
These need factual education.</td>
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<td colspan="2" align="left" valign="middle"><strong>Evolution 						  as a process is composed of two parts:</strong></td>
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<td width="20">&nbsp;</td>
<td><strong>1. An organism reproducing mechanism that provides 						  variable organisms.</strong> Changes to the organism are largely random and effect 						  future generations. They are made without regard to consequences to the 						  organism.</td>
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<td width="20">&nbsp;</td>
<td><strong>2. A changing environment which screens organism 						  changes. </strong>The environment provides stress on the variable organisms that 						  selectively allows, through competition, certain changes to become dominant and 						  certain others to be eliminated, without consideration for the future of the 						  mechanism. That same process provides mechanism (organism) disintegration if a 						  strong screening environment is not present. Evolution is a two-way process 						  which does not always work to the long term advantage of the organism and in 						  fact often becomes quite deadly to a given species and thereby eradicates 						  it.</td>
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<p>The evolutionary process is bidirectional in its effect. It may, 				  depending on the environment, either improve a given characteristic or decay 				  it. Since the first step in the process is largely random and most organisms 				  are quite complex, almost all of the variations are harmful. A characteristic 				  of a species advances if the environment is harsh, since most harmful 				  variations to that characteristic will be eliminated through death and 				  suffering at a rapid rate, leaving only the inconsequential and helpful changes 				  in the lineage. If the environment is benign with respect to the capability of 				  the species then the harmful changes are not eliminated and the species will 				  degenerate to a point of balance with the environment.</p>
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